Functional Deimmunization of Interferon Beta-1b by Identifying and Silencing Human T Cells Epitopes
نویسندگان
چکیده
منابع مشابه
The Effect of Beta Interferon on Dendritic Cells and Cytokine Synthesis by CD4+ T Cells
Background: Dendritic cells (DC) are a key regulator of the immune response, and interferon- beta (IFN-β) is considered an immunomodulatory molecule for DC. Objective: The purpose of this study was to evaluate the ability of IFN-β treated DC to induce cytokine secretion by CD4+ T cells. Methods: Dendritic cells were generated from blood monocytes with granulocyte-monocyte colony-stimulating fac...
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background: dendritic cells (dc) are a key regulator of the immune response, and interferon- beta (ifn-β) is considered an immunomodulatory molecule for dc. objective: the purpose of this study was to evaluate the ability of ifn-β treated dc to induce cytokine secretion by cd4+ t cells. methods: dendritic cells were generated from blood monocytes with granulocyte-monocyte colony-stimulating fac...
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ژورنال
عنوان ژورنال: Iranian Journal of Allergy, Asthma and Immunology
سال: 2019
ISSN: 1735-5249,1735-1502
DOI: 10.18502/ijaai.v18i4.1421